Welcome to the scan-x search page.
scan-x is a software tool designed to find motifs (identified using motif-x)
within any sequence data set.
The first large scale scan was performed using all available human, mouse, fly and yeast phosphorylation
and acetylation data to perform a scan for undiscovered modification sites. |
Please cite the following:
Chou MF & Schwartz D (2011). Using the scan-x Web site to predict protein post-translational modifications. Curr Protoc Bioinformatics. Chapter 13:Unit 13.16. doi:10.1002/0471250953.bi1316s36.
PDF (608K) | PubMed
Schwartz D, Chou MF and Church GM (2009). Predicting protein post-translational modifications using meta-analysis of proteome-scale data sets. Mol Cell Proteomics 8(2):365-79.
PDF (2.4 M) | Supplemental Data | PubMed
Using a part of the gene name, or a short unique fragment from your protein of interest, you may search our current prediction results for phosphorylation on your favorite proteins from Human, Mouse, Drosophila and Yeast protein databases, and for acetylation on Human protein databases. As described in the paper, each data set contains predicted hits at a certain level of specificity. Generally speaking, the higher the specificity, the lower the sensitivity and vice versa. The total number of predictions for each data set as of February 2009 are described in the text of the paper.
By clicking the 'Search' button, you certify that you meet the requirements specified by the following disclaimer: The software provided on this website may be used freely by users from academic and non-profit organizations. Users from the commercial sector should contact Daniel Schwartz (daniel.schwartz(at)uconn.edu).
|website created by Michael Chou and Daniel Schwartz (Church Lab)
© 2005-2008 The President and Fellows of Harvard College.